Assignment: Knee Pain and Inflammation

Assignment: Knee Pain and Inflammation

Assignment: Knee Pain and Inflammation

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Jonathon is a 56 year-old retired automobile mechanic who has not been to the doctor in approximately 6-7 years. He presents to your office complaining that 3 weeks ago he was awoken with severe pain and inflammation in his knee, which has been consistent since that initial night. Upon physical examination of his knee, it appears swollen and erythematous with periarticular involvement. Upon physical examination and laboratory results you notice the following:

Physical examination:

GEN: well nourished, obese male (310 pounds)

VS: BP 191/112 HR 75 RR 15 T 98.6, HT 5’8”

EXT: Knee joint inflammation

Laboratory (fasting):

Na 139 mEq/L

K 3.8 mEq/L

Ca 9.1 mg/dL

CL 102 mmol/L

HCO3 22 mEq/L

BUN 10 mg/dL

SCr 0.9 mg/dL

Serum Uric Acid 6.5 mg/dL

Alb 4.1 g/dL

Cholesterol 300 mg/dL

UA: pH 6.8, uric acid 250 mg/24h

What problems can be identified in this patient? Please provide a list of differential diagnoses, as well as indication of your primary diagnosis.What is your pharmacological plan for your primary diagnosis including the medication, dose, and mechanism of action?

Question 2

Discussion Part One (graded)

C.G. is a 69-year-old male with a history of right head and neck cancer that you have been following for one year. The carcinoma was initially localized to the head and neck-specifically at the left lingual tonsil region and went on to complete a total of 6 weeks of radiation and chemotherapy. Recently, the last PET scan indicated some metabolic activity in the left lymph node area along with other regions of abnormal metabolic activity in the body-particularly the liver and the lungs indicating metastasis. C.G. indicates that he is tired of the effects of chemotherapy and radiation and does not want to pursue any more treatment for cancer.

Background:

Right head and neck cancer with metastasis to liver and lungs; patient is refusing further treatment.

PMH:

Hypertension

Hyperlipidemia

Stomatitis

Anemia

Neutropenia

Current medications:

Carvedilol 12.5 mg po 1 daily

Furosemide 40 mg po daily

Surgeries:

2012: right radical neck dissection

Allergies:

None

Vaccination History:

Influenza vaccine last received 1 year ago

Received pneumovax at age 65

Received Tdap 5 years ago

Has not had the herpes zoster vaccine

Social history and Risk Factors:

Former smoker-stopped smoking at the time his cancer was diagnosed-2 years ago

Negative for alcohol intake or drug use

Patient does not have an advanced directive or living will. He is refusing further treatment for his cancer and his wife and children are in disagreement with him. The patient wants to know what his options are for the remainder of his life.

Family history:

Negative

Discussion Part One:

Provide differential diagnoses (DD) with rationale.

Further ROS questions needed to develop DD.

Identify the legal/ethical issues involved with the patient and describe your approach to addressing end-of-life care for this patient.

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