Assignment: SCI115 Week6 Discussion-STR
Assignment: SCI115 Week6 Discussion-STR
Assignment: SCI115 Week6 Discussion-STR
Assignment: SCI115 Week6 Discussion-STR
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SCI 115 Week 6 Discussion STR
Discussion
Pedigrees for Topics 1 and 2. A document in this week’s Instructor Insights folder contains the pedigree for three different traits from the same family. Each pedigree follows the usual conventions for pedigrees: squares are male; circles are female; offspring are drawn under each mating pair. Individuals with the trait are shaded. See the textbook for more information about pedigrees.
Topic 1. Pedigree for Trait 1. Suppose that we are certain that Trait 1 follows a Mendelian pattern of inheritance and that Trait 1 is an autosomal dominant trait. Suppose further that the dominant allele is designated as A and the recessive allele is a.
(a) Determine the genotype of Alan Blue and explain how you determined it. Go through your logic and reasoning step by step.
(b) If we were wagering on the genotype of Harlan Brown, what genotype would you put your money on? Explain.
Topic 2. Pedigrees for Trait 2. Suppose that we are certain that Trait 2 follows a Mendelian pattern of inheritance and that Trait 2 is an autosomal recessive trait. Suppose further that the the dominant allele is B and the recessive allele is b.
(a) Determine the genotype of Alan Blue and explain how you determined it. Go through your logic and reasoning step by step.
(b) Determine the genotype of Denise Hawk and explain how you determined it. Go through your logic and reasoning step by step.
Topic 3. Esvelt’s Regret. In the article by Zimmer (1), Kevin Esvelt says that he made a huge mistake by championing the application of a technology that he now says is far too dangerous to actually deploy. In a post of about 125 words, address the following:
(a) What is the technology that Esvelt championed? What does this technology do? Why does he think it’s too risky to use outside the lab?
(b) In your opinion, what sorts of laws and regulations, if any, should society put into place to regulate the technology that Esvelt regrets championing?
Topic 4. Societal Aspects of Human Gene Editing. Read the article by Neuhaus (2) and/or the article by Ossola, then address the following:
(a) Where do you think our procedures, regulations and laws ought to come down regarding human genome editing, with CRISPR (or any other tool)? Take a clear position on this.
(b) Explain your rationale.
References
Carl Zimmer, November 16, 2017, ‘Gene drives’ are too risky for field trials, scientists say, https://www.nytimes.com/2017/11/16/science/gene-drives-crispr.html?_r=0
Carolyn P. Neuhaus, March 16, 2017, Genome editing: bioethics shows the way. http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2001934
Alexandra Ossola, August 6, 2015, Should bioethicists “get out of the way” of CRISPR research?, https://www.popsci.com/should- bioethicists-get-out-way-crispr-research
You must proofread your paper. But do not strictly rely on your computer’s spell-checker and grammar-checker; failure to do so indicates a lack of effort on your part and you can expect your grade to suffer accordingly. Papers with numerous misspelled words and grammatical mistakes will be penalized. Read over your paper – in silence and then aloud – before handing it in and make corrections as necessary. Often it is advantageous to have a friend proofread your paper for obvious errors. Handwritten corrections are preferable to uncorrected mistakes.
Use a standard 10 to 12 point (10 to 12 characters per inch) typeface. Smaller or compressed type and papers with small margins or single-spacing are hard to read. It is better to let your essay run over the recommended number of pages than to try to compress it into fewer pages.
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The paper must be neatly formatted, double-spaced with a one-inch margin on the top, bottom, and sides of each page. When submitting hard copy, be sure to use white paper and print out using dark ink. If it is hard to read your essay, it will also be hard to follow your argument.
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