Identify a strategy to account for variability in fucpoaphine activation that can be used in a pre-hospital situation and briefly explain how this strategy could be used to optimise treatment response and tolerability.
Coursework Medicine and Health Paper , Order, or Assignment Requirements Systemic Clearance Extended Calculation A pharmaceutical company is developing a new drug ‘FCP-17′ and has just determined the following pharmacokinetic parameters from a Phase I human study: Fraction unbound (fu): 0.5 Clearance by active secretion (CLsec): 2L/hr Fraction reabsorbed (FR): 0.25 Hepatic Extraction Ratio (EH): […]
