In the introduction of your paper, present a brief paragraph that describes and and explains the importance of of your topic, and its relevance to the criminal justice community and to society.
In the body of your paper, discuss the nature of your topic in detail. Discuss to whom the topic is of direct importance, how it is used, when and how it is used in the courtroom, the actors are that are involved, etc… Discuss any court challenges to the topic and any relevant court rulings. Be sure to use academic, scientific, statistical or government resources to expand information about the topic you select.
Conclude with a summary paragraph highlighting the main points of your topic, and emphasizing the relevance to the criminal justice community.
If you have any question about your topic, contact your instructor before you begin.
The final paper is due by day 1 of Week/Module 15 (April 20).

Case 1
HISTORY: Patient Presentation
A four-year-old African American male diagnosed with sickle cell disease in the newborn period was admitted to the hospital with abdominal pain. Two days prior to admission, he was seen in the emergency room for abdominal pain and sent out on pain medicine.
PHYSICAL EXAM
Height 100 cm (25th percentile on growth chart)
Weight 15 kg (25th percentile on growth chart)
Temperature: 38.9ºC
Heart Rate: 135
Respiratory Rate: 40
Blood Pressure 100/60 mmHg
Oxygen Saturation Level: 87% (normal range: 92%-98%)

HEENT: Normocephalic, pupils reactive, tympanic membranes clear, oropharynx clear
Neck: No adenopathy
Chest: Mild subcostal retractions. Audible rales at lung bases.
Heart: Tachycardic with III/VI murmur
Abdomen: Mild distension, diffusely tender to palpation
Genitourinary: Circumcised male, no priapism
Extremities: Warm
Neurologic: Crying, alert boy. Face was symmetric. Moved all extremities.

LABORATORY DATA
Patient Value Normal Value
WBC 15,000 4,000-12,000/μL
HGB 6.3 11.5-13.5 g/dL
HCT 18 34%-40%
PLT 560,000 140,000-440,000/μL
MCV 89.0 75-87 fl
Retic % 14% 0.5%-1.5%
Rectic Absolute 0.2125 0.024-0.084 M/μL

1 What history, including symptoms, would be most helpful in evaluating this patient?
2 What does a prior history of abdominal pain reflect? What does Bone pain and swollen, painful fingers (dactylitis) reflect in this disease?
3 He had a temperature of 101 degrees Fahrenheit yesterday.what does that indicate?
4 He has been coughing 2-3 times a day and intermittently through the night.what does that indicate??
5 Does family history indicate sickle disease?
6 What additional physical findings might occur in patients with sickle cell disease? Discuss Jaundice and Splenomagaly??
7 What other labs would you request? Compare the lab findings with normal ranges
Discuss Peripheral smear, hemoglobin electrophoresis,
Blood culture; Blood Type and screen for antibodies
LDH; Haptoglobin levels
Amylase and Lipase
8 Discuss MCV, MCH, RDW, ESR, Hematocrit and red cell morphology in this disease
9 What was your differential diagnosis when you first saw the patient? Discuss the following in diagnosing the disease
Cholecystitis; Pneumonia; Upper respiratory tract infection; Vaso-occlusive pain crisis
10 what are the differences between sickle cell disease, HbC, HbE and Thalassemia diseases?
11 Discuss Iron deficiency anemia, thalassemia syndromes and sickle cell anemia
12 How would you treat this patient?

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